HMGA2 Polyclonal Antibody


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Cat.No.:  EAb-3385
Product Name:  HMGA2 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  A synthetic peptide of human HMGA2
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  13kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  COLO320
Species Reactivity:  Human
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot P52926; Gene ID 8091
Alternative Name:  HMGA2; BABL; HMGI-C; HMGIC; LIPO; STQTL9; high mobility group AT-hook 2
Scientific Background:  This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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