HAT1 Polyclonal Antibody


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Cat.No.:  EAb-3330
Product Name:  HAT1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  A synthetic peptide of human HAT1
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  47kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:500 - 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  Jurkat
Species Reactivity:  Human
Storage:  4℃.
Storage Buffer:  PBS with 0.02% sodium azide, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot O14929; Gene ID 8520
Alternative Name:  HAT1; KAT1; histone acetyltransferase 1
Scientific Background:  The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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