DNMT3A Polyclonal Antibody


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Cat.No.:  EAb-3326
Product Name:  DNMT3A Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein of human DNMT3A
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  95kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB; IHC; IF
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  Mouse spleen,Mouse skeletal muscle
Species Reactivity:  Human, Mouse, Rat
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot Q9Y6K1; Gene ID 1788
Alternative Name:  DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3 alpha
Scientific Background:  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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