Cat.No.: | EAb-3273 |
Product Name: | SETDB2 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SETDB2 |
Immunogen Sequence: | MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEATIINSSTSIKDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDS |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 82kDa |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB |
Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | HL-60,Mouse thymus,Rat heart |
Species Reactivity: | Mouse, Rat |
Storage: | -20℃. |
Storage Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Swiss Prot Q96T68; NP_001153780.1; Gene ID 83852 |
Alternative Name: | SETDB2; C13orf4; CLLD8; CLLL8; KMT1F; SET domain bifurcated 2 |
Scientific Background: | This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
◆ Antibodies | ||
EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
SENP3 | SENP8 | SET | SET1 |
SET2 | SET7 | SET8 | SET9 |
SETBP1 | SETD1A | SETD1B | SETD2 |
SETD3 | SETD5 | SETD6 | SETD7 |
SETD8 | SETD9 | SetDB1 | SETDB2 More > |
SETMAR |
USA
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