RNF2 Polyclonal Antibody


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Cat.No.:  EAb-3267
Product Name:  RNF2 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  A synthetic peptide of human RNF2
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  37kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:200 - 1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  U-87MG,K-562,NIH/3T3,U-937
Species Reactivity:  Human, Mouse
Storage:  4℃.
Storage Buffer:  PBS with 0.02% sodium azide, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot Q99496; Gene ID 6045
Alternative Name:  RNF2; BAP-1; BAP1; DING; HIPI3; RING1B; RING2; ring finger protein 2
Scientific Background:  Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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