| Cat.No.: | EAb-3214 |
| Product Name: | Dnmt3L Monoclonal Antibody (N117/9) |
| Product Overview: | Mouse monoclonal (N117/9) to detect Dnmt3L |
| Antibody Type: | Monoclonal |
| Clone Designation: | N117/9 |
| Immunogen: | Fusion protein, corresponding to amino acids 1-387 of Human Dnmt3L. |
| Host: | Mouse |
| Isotype: | IgG1 |
| Purification: | Protein G purified |
| Appearance: | Liquid |
| Formulation: | 0.09% Sodium Azide |
| Applications: | WB, IHC-P, ICC/IF, IHC-Fr |
| Species Reactivity: | Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | BAA95556 |
| Alternative Name: | Cytosine 5 methyltransferase 3 like protein antibody/DNA (cytosine 5 ) methyltransferase 3 like antibody/DNA (cytosine-5)-methyltransferase 3-like antibody |
| Scientific Background: | Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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