Cat.No.: | EAb-3103 |
Product Name: | Histone H1 Monoclonal Antibody (r1415-1) |
Product Overview: | Mouse monoclonal (r1415-1) to detect Histone H1 |
Antibody Type: | Monoclonal |
Clone Designation: | r1415-1 |
Immunogen: | Other Immunogen Type corresponding to Human Histone H1. Nuclei of human leukemia biopsy cells. |
Host: | Mouse |
Isotype: | IgG2a |
Purification: | Protein A/G purified |
Appearance: | Liquid |
Formulation: | 0.05% Sodium azide, 99% PBS, 0.05% BSA |
Applications: | IHC-P |
Species Reactivity: | Rat, Human |
Storage: | -20°C. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | SwissProt 226117 & 97358 |
Alternative Name: | dJ221C16.2 antibody/dJ221C16.5 antibody/DmeH1 antibody |
Scientific Background: | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. |
Product Types | ||
◆ Nucleosomes | ||
NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
◆ Synthetic Peptides | ||
SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
SP-0010 | Histone H4 peptide (1-21) | Inquiry |
SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
Related Gene / Proteins | |||
HIC1 | HIF1A | HIF1AN | HINFP |
HIPK1 | HIPK2 | HIRA | Histone |
Histone H1 | Histone H2A | Histone H2B | Histone H3 |
Histone H4 | HIV-1 reverse transcriptase |
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