Histone H1 Monoclonal Antibody - Azide and BSA free


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Cat.No.:  EAb-3080
Product Name:  Histone H1 Monoclonal Antibody - Azide and BSA free
Product Overview:  Mouse monoclonal to detect Histone H1 - Azide and BSA free
Antibody Type:  Monoclonal
Immunogen:  Recombinant full length protein corresponding to Human Histone H1.
Host:  Mouse
Isotype:  IgG2a
Purification:  Protein A purified
Appearance:  Liquid
Formulation:  100% PBS
Applications:  IHC-P
Species Reactivity:  Rat, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  P07305
Alternative Name:  dJ221C16.2 antibody/dJ221C16.5 antibody/DmeH1 antibody
Scientific Background:  May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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