SETD1B Polyclonal Antibody


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Cat.No.:  EAb-2604
Product Name:  SETD1B Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect SETD1B
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human SETD1B aa 350-400.
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, 99% Tris citrate/phosphatepH 7 to 8
Applications:  IHC-P, WB, IP
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  23067
Alternative Name:  FLJ20803 antibody/Histone-lysine N-methyltransferase SETD1B antibody/hSET1B antibody
Scientific Background:  Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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