PARP1 Polyclonal Antibody


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Cat.No.:  EAb-2603
Product Name:  PARP1 Polyclonal Antibody
Product Overview:  Chicken polyclonal to detect PARP1
Antibody Type:  Polyclonal
Immunogen:  Recombinant full length protein corresponding to Human PARP1. Highly purified human PARP1 expressed in baculovirus.
Host:  Chicken
Isotype:  IgY
Purification:  IgY fraction
Appearance:  Liquid
Formulation:  pH: 7.40; 0.02% Sodium azide, 0.87% Sodium chloride, 0.316% Tris HCl
Applications:  WB, ELISA
Species Reactivity:  Mouse, Rat, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) antibody/ADP ribosyltransferase antibody/ADP ribosyltransferase diphtheria toxin like 1 antibody
Scientific Background:  Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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  • Tel: 1-631-559-9269 / 1-516-512-3133
  • Fax: 1-631-938-8127
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