PRMT2/HMT1 Polyclonal Antibody


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Cat.No.:  EAb-2602
Product Name:  PRMT2/HMT1 Polyclonal Antibody
Product Overview:  Goat polyclonal to detect PRMT2/HMT1
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human PRMT2/HMT1 aa 118-131 (internal sequence) (Cysteine residue).
Immunogen Sequence:  DQPRTTKYHSVILQ
Host:  Goat
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.30; 0.02% Sodium azide, 99% Tris buffered saline, 0.5% BSA
Applications:  WB
Species Reactivity:  Mouse, Rat, Human, Pig
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  ANM2_HUMAN antibody/EC 2.1.1. antibody/histone arginine N methyltransferase PRMT2 antibody
Scientific Background:  Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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