hSET1/SET1 Polyclonal Antibody


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Cat.No.:  EAb-2490
Product Name:  hSET1/SET1 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect hSET1/SET1
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human hSET1/SET1.
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, Tris citrate/phosphate
Applications:  IHC-P, ChIP, ChIP/Chip, WB, IP, ICC/IF
Species Reactivity:  Mouse, Rat, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  O15047
Alternative Name:  Histone-lysine N-methyltransferase SETD1A antibody/hSET1A antibody/KMT2F antibody
Scientific Background:  Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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