| Cat.No.: | EAb-2484 |
| Product Name: | Keap1 Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect Keap1 |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to 19 amino acids near the C-terminus of Human Keap1 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | 0.02% Sodium azide, 99% PBS |
| Applications: | WB, ICC/IF |
| Species Reactivity: | Mouse, Rat, Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | NP_987096 |
| Alternative Name: | Cytosolic inhibitor of Nrf2 antibody/INrf 2 antibody/INrf2 antibody |
| Scientific Background: | Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0320 | KEAP1 Polyclonal Antibody | Inquiry |
| EAb-0397 | KEAP1 Polyclonal Antibody | Inquiry |
| EAb-1323 | KEAP1 Polyclonal Antibody, HRP Conjugated | Inquiry |
| EAb-1324 | KEAP1 Polyclonal Antibody, FITC Conjugated | Inquiry |
| EAb-1325 | KEAP1 Polyclonal Antibody, Biotin Conjugated | Inquiry |
| Related Gene / Proteins | |||
| KEAP1 | |||
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