SUV3L1 Polyclonal Antibody


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Cat.No.:  EAb-2445
Product Name:  SUV3L1 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect SUV3L1
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide within Human SUV3L1 aa 736-786 (C terminal).
Immunogen Sequence:  RLVQQ GLLTPDMLKQ LEKEWMTQQT EHNKEKTESG THPKGTRRKK
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, 99% Tris buffered saline, 0.1% BSA
Applications:  IP, WB
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  NP_003162.2
Alternative Name:  6330443E10Rik antibody/ATP dependent RNA helicase SUPV3L1, mitochondrial antibody/ATP-dependent RNA helicase SUPV3L1 antibody
Scientific Background:  Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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