Cat.No.: | EAb-2424 |
Product Name: | MCM6 Polyclonal Antibody |
Product Overview: | Rabbit polyclonal to detect MCM6 |
Antibody Type: | Polyclonal |
Immunogen: | Synthetic peptide corresponding to Human MCM6 aa 589-605 (internal sequence). |
Immunogen Sequence: | ESEDFIVEQYKHLRQRD |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Immunogen affinity purified |
Appearance: | Liquid |
Formulation: | 0.025% Thimerosal (merthiolate), 0.025% Sodium azide, 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate |
Applications: | IHC-P, IHC-Fr, ICC/IF, WB, ICC |
Species Reactivity: | Mouse, Rat, Human |
Storage: | -20°C. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q14566 |
Alternative Name: | DNA replication licensing factor MCM6 antibody/MCG40308 antibody/Mcm6 antibody |
Scientific Background: | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. |
Product Types | ||
◆ Cell Lines | ||
CL-0011 | Human MCF2L Knockout Cell Line | Inquiry |
◆ Antibodies | ||
EAb-0068 | MCAF Polyclonal Antibody | Inquiry |
EAb-0303 | MCM6 Polyclonal Antibody | Inquiry |
◆ Extracts & Lysates | ||
EL-0161 | Recombinant Human MCRS1 293 Cell Lysate | Inquiry |
◆ Proteins & Enzymes | ||
PE-1225 | Recombinant Human MCRS1, His-tagged | Inquiry |
Related Gene / Proteins | |||
MCAF1 | MCF2L | MCM6 | MCM8 |
MCRS1 |
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