| Cat.No.: | EAb-2420 |
| Product Name: | HP1-gamma/CBX3 Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect HP1 gamma/CBX3 |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant fragment within Human HP1 gamma/CBX3 (internal sequence). |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | pH: 7.00; 0.01% Thimerosal (merthiolate), PBS, 1% BSA, 20% Glycerol |
| Applications: | WB, ICC/IF, IP, IHC-P |
| Species Reactivity: | Mouse, Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q13185 |
| Alternative Name: | CBX 3 antibody/CBX3 antibody/CBX3_HUMAN antibody |
| Scientific Background: | Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0051 | Human CBX1 Knockout Cell Line 32bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0082 | HP1α, β and γ Polyclonal Antibody | Inquiry |
| EAb-0083 | HP1α Polyclonal Antibody | Inquiry |
| EAb-0149 | CBX1 Polyclonal Antibody | Inquiry |
| EAb-0677 | CBX1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| HP1 | HP1BP3 | ||
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