| Cat.No.: | EAb-2416 |
| Product Name: | HP1-alpha Polyclonal Antibody - ChIP Grade |
| Product Overview: | Goat polyclonal to detect HP1 alpha - ChIP Grade |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to internal sequence amino acids 88-102 of Human HP1 alpha |
| Immunogen Sequence: | C-NKRKSNFSNSADDIK |
| Host: | Goat |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | pH: 7.30; 0.02% Sodium azide, 0.5% BSA, 0.5% Tris buffered saline |
| Applications: | ICC/IF, IP, IHC-P, ChIP, WB |
| Species Reactivity: | Mouse, Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | NP_036249.1 |
| Alternative Name: | Antigen p25 antibody/CBX5 antibody/CBX5_HUMAN antibody |
| Scientific Background: | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0051 | Human CBX1 Knockout Cell Line 32bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0082 | HP1α, β and γ Polyclonal Antibody | Inquiry |
| EAb-0083 | HP1α Polyclonal Antibody | Inquiry |
| EAb-0149 | CBX1 Polyclonal Antibody | Inquiry |
| EAb-0677 | CBX1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| HP1 | HP1BP3 | ||
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