| Cat.No.: | EAb-2401 |
| Product Name: | SATB2 Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect SATB2 |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic 14 amino acid peptide near the carboxy terminus of the human SATB2. |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | 0.02% Sodium azide, PBS |
| Applications: | ICC/IF, IHC-P, WB |
| Species Reactivity: | Mouse, Rat, Human |
| Storage: | +4°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9UPW6 |
| Alternative Name: | DNA binding protein SATB2 antibody/DNA-binding protein SATB2 antibody/FLJ21474 antibody |
| Scientific Background: | Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0034 | SALL1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0058 | 3-Deazaadenosine | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0152 | Recombinant Human SAP30L 293 Cell Lysate | Inquiry |
| EL-0155 | Recombinant Human SAP30BP 293 Cell Lysate | Inquiry |
| EL-0164 | Recombinant Human SAP30 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SAH | SALL1 | SALL4 | SAP130 |
| SAP145 | SAP18 | SAP30 | SAP30BP |
| SAP30L | SART3 | SATB1 | SATB2 |
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