| Cat.No.: | EAb-2374 |
| Product Name: | EED Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This EED antibody was raised against full-length recombinant human EED protein. |
| Host: | Mouse |
| Isotype: | IgG2a |
| Molecular Weight: | 57 kDa |
| Purification: | Protein A Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP: 4 µl per ChIP; ChIP-Seq: 4 µl each; IHC: 2 - 8 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O75530 |
| Alternative Name: | EED; HEED; WAIT1; polycomb protein EED |
| Scientific Background: | EED (extraembryonic ectoderm) is a component of the Polycomb group (PcG) multiprotein complex PRC2. The PRC2 complex also contains EZH2 and SUZ12 and is recruited to Polycomb response elements and results in the methylation of histone H3 and lysine 27 and the silencing of gene expression. PRC2 initiates repression of the Hox genes during development and is involved in the maintenance of stem cell pluripotency. EED is a member of the superfamily of WD-40 repeat protein family and is required for PRC2-mediated H3K27 methylation. The PRC2 complex may also recruit platform DNMTs, thereby linking two systems of epigenetic repression. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0026 | Recombinant Human EED Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0166 | MAK-683 | Inquiry |
| ◆ Research Kits | ||
| EKIT-0182 | EZH2-EED Binding Assay Kit | Inquiry |
| ◆ Antibodies | ||
| EAb-0196 | EEF1A Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0248 | Recombinant Human EED, His & GST tagged | Inquiry |
| Related Gene / Proteins | |||
| EED | EEF1A1 | EEF1A2 | EEF1B2 |
| EEF1G | |||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
