Ubiquitin Monoclonal Antibody


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Cat.No.:  EAb-2291
Product Name:  Ubiquitin Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This Ubiquitin antibody was raised against purified bovine ubiquitin.
Host:  Mouse
Isotype:  IgG
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.
Applications:  WB
Species Reactivity:  Human, Wide Range Predicted
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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