ASH2L Monoclonal Antibody


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Cat.No.:  EAb-2135
Product Name:  ASH2L Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.
Host:  Rat
Isotype:  IgG2a
Molecular Weight:  85 kDa
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IP; ICC/IF; IHC; WB
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  ASH2L (absent, small, or homeotic)-like (Drosophila) is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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