| Cat.No.: | EAb-2103 |
| Product Name: | L3MBTL2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This L3MBTL2 antibody was raised against a His-Tagged fusion protein containing amino acids 1-230 of human L3MBTL2. |
| Host: | Rabbit |
| Isotype: | Serum |
| Molecular Weight: | 90 kDa |
| Purification: | None |
| Appearance: | Liquid |
| Formulation: | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Applications: | IP: 10 µl per IP; WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0070 | L3MBTL1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0077 | Recombinant Human L3MBTL1 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0097 | Human L3MBTL2 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0244 | UNC 1215 | Inquiry |
| BSM-0245 | UNC-669 | Inquiry |
| Related Gene / Proteins | |||
| L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 |
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