Cat.No.: | EAb-2098 |
Product Name: | Lamin B1 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This Lamin B1 antibody was raised against a full-length protein corresponding to human Lamin B1. |
Host: | Rabbit |
Isotype: | Serum |
Molecular Weight: | 66-70 kDa |
Purification: | None |
Appearance: | Liquid |
Formulation: | Rabbit serum containing 0.1% sodium azide. |
Applications: | WB: 1:100 - 1:500 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human, Mouse |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | Lamin B1 (LMN, ADLD), along with the A and C Lamins are involved in maintaining the spatial organization of nuclear compartments. Depletion of Lamin B1 results in the disruption of RNA synthesis by RNA pol II, and eventually migration of chromatin to the nuclear periphery and dispersion of the nucleoli. The role of Lamin B1 in maintaining the nucleoskeleton may be to bind to nucleophosmin/B23. |
Product Types | ||
◆ Cell Lines | ||
CL-0180 | Human LASP1 Knockout Cell Line | Inquiry |
◆ Antibodies | ||
EAb-1284 | LAS1L Polyclonal Antibody, HRP Conjugated | Inquiry |
EAb-1286 | LAS1L Polyclonal Antibody, FITC Conjugated | Inquiry |
EAb-1288 | LAS1L Polyclonal Antibody, Biotin Conjugated | Inquiry |
EAb-1295 | LAS1L Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
Lamin A | Lamin B1 | LARP1 | LARP7 |
LAS1L | LASP1 |
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