Androgen Receptor Polyclonal Antibody


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Cat.No.:  EAb-2078
Product Name:  Androgen Receptor Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This Androgen Receptor antibody was raised against a peptide in the N-terminal region of human Androgen receptor.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  110 kDa
Purification:  Protein A Chromatography
Appearance:  Liquid
Formulation:  PBS pH 7.5 containing 30% glycerol and 0.035% sodium azide.
Applications:  ChIP: 5 µg per ChIP; ChIP-Seq: 5 µg each; WB: 1 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Androgen Receptor (AR, NR3C4) is a nuclear receptor that facilitates signaling of testosterone and other androgenic hormones in the cytoplasm and translocates into the nucleus upon hormone binding. AR serves as a DNA binding activator of transcription of hormone responsive genes. There are two forms of the Androgen Receptor, the AR-A form, lacking the N-terminal 187 amino acids and the full length AR-B form. Androgen Receptor is involved in the development of both primary and secondary male sexual characteristics and abnormal expression of AR is linked to prostate cancer.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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