| Cat.No.: | EAb-2070 |
| Product Name: | Bcl3 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This Bcl3 antibody was raised against a peptide within the C-terminal half of human Bcl3. |
| Host: | Rabbit |
| Isotype: | Serum |
| Molecular Weight: | 60 kDa |
| Purification: | None |
| Appearance: | Liquid |
| Formulation: | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Bcl3 (B-cell lymphoma 3 protein) functions as a transcriptional co-activator that activates through its association with NFkB homodimers. Bcl3 contains seven ankyrin repeats, which are most closely related to those found in IkB proteins. Bcl3 also functions as a form of IkB< specific for the NFκB p50 subunit inhibiting its translocation to the nucleus. The expression of this gene can be induced by NFκB, which forms a part of the autoregulatory loop that controls the nuclear residence of NFκB p50. Bcl3 is overexpressed in a number of cancers, can transform fibroblasts and induce tumors in nude mice, thus implicating Bcl3 as a proto-oncogene. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0087 | Recombinant Human BCOR 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0708 | Recombinant Human BCOR, GST-tagged | Inquiry |
| PE-0709 | Recombinant Zebrafish BCOR | Inquiry |
| PE-0710 | Recombinant Mouse BCOR Protein | Inquiry |
| PE-0711 | Recombinant Human BCOR Protein, GST-tagged | Inquiry |
| Related Gene / Proteins | |||
| Bcl10 | BCL11A | Bcl3 | Bcl6 |
| BCOR | |||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
