| Cat.No.: | EAb-2062 |
| Product Name: | RING1B Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This Ring1B antibody was raised against the recombinant full-length mouse protein. |
| Host: | Mouse |
| Isotype: | IgG2b |
| Molecular Weight: | 40 kDa |
| Purification: | Protein G Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP-Seq: 4 µl each; ChIP; IP; ICC/IF; WB^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Monkey, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Ring1B (also known as ring finger protein 2, RING2 or RNF2) is an essential component of the Polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is important for the transcriptional repression of genes involved in development and cell proliferation, such as the Hox genes. Ring1B also acts as an E3 ubiquitin ligase on histone H2A of the PRC1 complex. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0119 | Human RING1 Knockout Cell Line 1bp deletion | Inquiry |
| CL-0401 | Human RIF1 Knockout Cell Line 37bp insertion | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0178 | Human RIG-I/DDX58 peptide | Inquiry |
| ◆ Antibodies | ||
| EAb-1750 | RING1 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1892 | RIZ1 (human recombinant) | Inquiry |
| Related Gene / Proteins | |||
| RIF1 | RIG-I | RING1 | RING1B |
| RIZ1 | |||
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