Bcl10 Monoclonal Antibody


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Cat.No.:  EAb-2054
Product Name:  Bcl10 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This Bcl10 antibody was raised against full-length recombinant human Bcl10 protein.
Host:  Mouse
Isotype:  IgG
Molecular Weight:  33 kDa
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.
Applications:  IP: 10 µg per IP; WB: 0.5 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Bcl10 (B-cell CLL/lymphoma 10) protein promotes apoptosis and activation of NFκB (NFκB p50 & NFκB p65) via NIK and IKK (IKKα, IKKβ, IKKi/IKKε and IKKγ). Bcl10 protein contains a caspase recruitment domain (CARD) which interacts with other CARD domain containing proteins to regulate NFκB signaling. It is also a substrate for MALT1.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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