Ddit3 Monoclonal Antibody


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Cat.No.:  EAb-2022
Product Name:  Ddit3 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This antibody was raised against full-length recombinant mouse Ddit3 protein.
Host:  Mouse
Isotype:  IgG2b
Molecular Weight:  29 kDa
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IP; WB
Species Reactivity:  Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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