Cat.No.: | EAb-2022 |
Product Name: | Ddit3 Monoclonal Antibody |
Antibody Type: | Monoclonal |
Immunogen: | This antibody was raised against full-length recombinant mouse Ddit3 protein. |
Host: | Mouse |
Isotype: | IgG2b |
Molecular Weight: | 29 kDa |
Purification: | Protein G Chromatography |
Appearance: | Liquid |
Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
Applications: | IP; WB |
Species Reactivity: | Mouse |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. |
Product Types | ||
◆ Antibodies | ||
EAb-0055 | Phospho-DDX3X (Thr322) Polyclonal Antibody | Inquiry |
EAb-0306 | DDX43 Polyclonal Antibody | Inquiry |
EAb-0307 | DDB2 Polyclonal Antibody | Inquiry |
◆ Extracts & Lysates | ||
EL-0057 | Recombinant Human DDX20 293 Cell Lysate | Inquiry |
◆ Synthetic Peptides | ||
SP-0178 | Human RIG-I/DDX58 peptide | Inquiry |
Related Gene / Proteins | |||
DDB2 | Ddit3 | DDX10 | DDX18 |
DDX20 | DDX28 | DDX3X | DDX41 |
DDX42 | DDX43 | DDX49 | DDX50 |
DDX58 |
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