SMYD3 Polyclonal Antibody


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Cat.No.:  EAb-2015
Product Name:  SMYD3 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This antibody was raised against a peptide within human Smyd3.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  50 kDa
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:500 - 1:1,000 dilutio; IHC (FFPE)^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Smyd3 (SET and MYND domain containing 3) is a histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Recently, Smyd3 was described as the methyltransferase responsible for a novel site of histone modification, H4K5 methylation,

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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