| Cat.No.: | EAb-1994 |
| Product Name: | c-Fos Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within human c-Fos. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 60 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | c-Fos (FBJ murine osteosarcoma viral oncogene homolog) is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| ◆ Antibodies | ||
| EAb-1913 | c-Myc Polyclonal Antibody (65 kDa form) | Inquiry |
| EAb-1914 | c-Myc Monoclonal Antibody | Inquiry |
| EAb-1941 | c-Jun Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1983 | C-jun Protein | Inquiry |
| Related Gene / Proteins | |||
| c-Fos | c-Jun | c-MET | c-Myc |
| c-RET | |||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
