SND1 Monoclonal Antibody


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Cat.No.:  EAb-1983
Product Name:  SND1 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This antibody was raised against a recombinant protein corresponding to amino acids 505 - 674 of human SND1.
Host:  Mouse
Isotype:  IgG1
Molecular Weight:  115 kDa
Purification:  Protein A Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IP; ICC/IF; IHC; WB
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  SND1 (staphylococcal nuclease and tudor domain containing 1) functions as a transcriptional coactivator and a modulator of RNA metabolism. As a transcriptional coactivator, it acts as a bridging factor between STAT6 and the basal transcription factors, plays a role in PIM1 regulation of MYB activity and is a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). SND-1 has been identified as part of the RISC complex (RNA-induced silencing complex) and interacts with Ago-2. It is involved in the degradation of hyper-edited inosine containing microRNA precursors as part of the RNA interference pathway.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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