| Cat.No.: | EAb-1979 |
| Product Name: | GATA-4 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This GATA-4 antibody was raised against a peptide derived from the C-terminus of human GATA-4. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 55 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | GATA-4 is a zinc finger protein and part of the GATA family of sequence specific DNA binding transcription factors that recognize a consensus DNA sequence containing GATA. GATA-4 is involved in the development of several mesodermal and endodermal structures. GATA-4 mutant mice exhibit severe heart malformations. Defects in GATA-4 are the cause of atrial septal defect type 2. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. GATA-4 also plays a role in regulating gene expression in cardiac and smooth muscle cell types. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0023 | Human GATAD2B Knockout Cell Line | Inquiry |
| CL-0202 | Human GABRG2 Knockout Cell Line | Inquiry |
| CL-0468 | Human GATAD2B Knockout Cell Line | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0292 | Gemcitabine | Inquiry |
| BSM-0378 | Gemcitabine-13C,15N2 (hydrochloride) | Inquiry |
| Related Gene / Proteins | |||
| GABRG2 | Gadd45a | GAR | GASC1 |
| GATA-1 | GATA-4 | GATA-6 | GATAD2A |
| GATAD2B | |||
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