| Cat.No.: | EAb-1974 |
| Product Name: | GLIS1 Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This antibody was raised against a peptide within the amino-terminal half of human GLIS1 (GLI-similar 1), which shares homology with mouse GLIS1. |
| Host: | Rat |
| Isotype: | IgG1k |
| Molecular Weight: | 95 kDa |
| Purification: | Protein G Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 0.5 - 2 µg/ml; IF: 1-2 µg/ml^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | GLIS1 (Glis Family Zinc Finger 1) belongs to a GLIS subfamily of Krüppel-like zinc-finger transcription factors characterized to regulate a set of downstream targets essential for cellular functions, including pancreatic development, β-cell maturation and maintenance, and insulin production. GLIS1 is enriched in unfertilized eggs and embryos and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells (iPS cells). GLIS1 may regulate the expression of numerous genes, either positively or negatively, and is implicated in mitral valve development, where dysregulation may lead to mitral valve prolapse (MVP). |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0192 | GLI1 Polyclonal Antibody | Inquiry |
| EAb-1974 | GLIS1 Monoclonal Antibody | Inquiry |
| EAb-1975 | GLI1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0408 | Thielavin B | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2516 | Recombinant Human GLYR1 protein | Inquiry |
| Related Gene / Proteins | |||
| GLI1 | GLI4 | GLIS1 | GliS2 |
| Glucose-6-phosphatase | GLYR1 | ||
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