| Cat.No.: | EAb-1948 |
| Product Name: | IRF-2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This IRF-2 antibody was raised against a peptide within the C-terminal region of human IRF-2. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 39 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | IRF-2 (interferon regulatory factor 2) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-1945 | IRF-5 Polyclonal Antibody | Inquiry |
| EAb-1946 | IRF-4 Polyclonal Antibody | Inquiry |
| EAb-1947 | IRF-3 Polyclonal Antibody | Inquiry |
| EAb-1948 | IRF-2 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2084 | Recombinant human PARP3/IRT1 protein | Inquiry |
| Related Gene / Proteins | |||
| IRF-2 | IRF-3 | IRF-4 | IRF-5 |
| IRT1 | |||
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