| Cat.No.: | EAb-1946 |
| Product Name: | IRF-4 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within the C-terminal region of human IRF-4. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 52 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | IRF-4 (Interferon Regulatory Factor 4) is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-1945 | IRF-5 Polyclonal Antibody | Inquiry |
| EAb-1946 | IRF-4 Polyclonal Antibody | Inquiry |
| EAb-1947 | IRF-3 Polyclonal Antibody | Inquiry |
| EAb-1948 | IRF-2 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2084 | Recombinant human PARP3/IRT1 protein | Inquiry |
| Related Gene / Proteins | |||
| IRF-2 | IRF-3 | IRF-4 | IRF-5 |
| IRT1 | |||
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