Cat.No.: | EAb-1934 |
Product Name: | TIEG1 / KLF10 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This TIEG1 / KLF10 antibody was raised against a peptide derived from human TIEG1 / KLF10. |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 50 kDa |
Purification: | Affinity Purified |
Appearance: | Liquid |
Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
Applications: | WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | TIEG1 / KLF10 (Transforming growth factor β-inducible early gene 1, Kruppel-like factor 10) is a transcriptional regulator involved in the control of cell growth. KLF10 binds to Sp1 / GC rich DNA sequences and can activate or repress the transcription of a number of genes. KLF10 is especially important for osteoblast function, including bone mineralization and support of osteoclast differentiation. KLF10 is rapidly induced by TGFβ, bone morphogenetic protein, estrogen and epidermal growth factor. KLF10 plays a major role in TGFβ-mediated inhibition of cell proliferation and inflammation and induction of apoptosis. |
Product Types | ||
◆ Antibodies | ||
EAb-0014 | TIP60 Polyclonal Antibody | Inquiry |
EAb-0015 | TIP60 Polyclonal Antibody | Inquiry |
◆ Proteins & Enzymes | ||
PE-1664 | TRIM24 (TIF1), GST-tag | Inquiry |
PE-1667 | TRIM24 (TIF1), His-tag | Inquiry |
PE-1887 | TIP60 (human recombinant) | Inquiry |
Related Gene / Proteins | |||
TIAL1 | TIEG1 | TIF1 | TIGD4 |
TIGD5 | TIP49A | TIP49B | TIP60 |
TIS11D |
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