| Cat.No.: | EAb-1914 |
| Product Name: | c-Myc Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein. |
| Host: | Rat |
| Isotype: | IgG2a |
| Molecular Weight: | 68 kDa |
| Purification: | Protein G Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | IP; EMSA; WB |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | c-Myc (Myc) is a sequence specific DNA binding transcription factor that regulates gene expression, especially genes involved in cell division. Myc family members contain a basic Helix-Loop-Helix leucine zipper (bHLHZ) domain. Myc family proteins associated with thousands of genes, especially those involved in cell growth and proliferation. c-Myc serves as an integrator of signal transduction, linking extracellular signals to an acute cellular growth response. Mutations and overexpression of c-Myc are associated with cell proliferation and cancer. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| ◆ Antibodies | ||
| EAb-1913 | c-Myc Polyclonal Antibody (65 kDa form) | Inquiry |
| EAb-1914 | c-Myc Monoclonal Antibody | Inquiry |
| EAb-1941 | c-Jun Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1983 | C-jun Protein | Inquiry |
| Related Gene / Proteins | |||
| c-Fos | c-Jun | c-MET | c-Myc |
| c-RET | |||
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