| Cat.No.: | EAb-1905 |
| Product Name: | NF-1A Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This NF-1A antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 478-492 of human NF-1A. |
| Host: | Rabbit |
| Isotype: | Serum |
| Molecular Weight: | 60 kDa |
| Purification: | None |
| Appearance: | Liquid |
| Formulation: | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Applications: | ICC/IF: 1:250 - 1:500 dilution; WB: 1:1,000 - 1:5,000 dilution; IHC^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | NF-1A (NF-1, Nuclear factor-1) is a ubiquitous 47 kDa dimeric DNA-binding protein whose recognition sequence, TGG(C/A)N(5)GCCAA, is found in the genomes of a number of DNA viruses. The same sequence occurs frequently in the human genome. The NF-1 protein stimulates initiation of adenovirus DNA replication in vitro and is capable of stimulating the transcription of genes in cooperation with other factors, such as the estrogen receptor. The Nuclear factor-1 (NF-1) family of transcription factors are encoded by the genes NF-1A, NF-1B2, NF-1C and NF-1X and feature a highly conserved N-terminal DNA binding region and a variable C-terminal transcriptional activation or repression domain. NF-1 binding controls the expression of many target genes, including insulin, TGF-β, nucleotide, steroid hormone and vitamin synthetic genes, TNFα and FSH. NF-1 transcripts can be differentially spliced and the resultant protein variants homo- and heterodimerize, allowing for multiple potential transcriptional activation and repression activities. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0201 | Recombinant Human NFKBIL2 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0294 | Wedelolactone | Inquiry |
| ◆ Antibodies | ||
| EAb-1903 | NFATC2 Polyclonal Antibody | Inquiry |
| EAb-1904 | NF-1B2 Polyclonal Antibody | Inquiry |
| EAb-1905 | NF-1A Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| NF-1A | NF-1B2 | NFATC2 | NFKBIL2 |
| NFκB | NFκB1 | NFκB3 | |
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