NonO Polyclonal Antibody


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Cat.No.:  EAb-1894
Product Name:  NonO Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This NonO antibody was raised against a peptide corresponding to the C-terminus of human NonO.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  60 kDa
Purification:  Protein A Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IP: 5 µg per IP; WB: 0.5 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  NonO (non-POU domain containing, octamer-binding, p54(nrb), NRB54, NMT55) is a DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. This gene also encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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