| Cat.No.: | EAb-1888 |
| Product Name: | NR3C1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within human NR3C1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 94 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | NR3C1 (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor)) is a receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0076 | Recombinant Human NR2E1 Cell Lysate | Inquiry |
| EL-0130 | Recombinant Human NRIP1 293 Cell Lysate | Inquiry |
| EL-0166 | Recombinant Human NR4A3 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0400 | Iberin | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0626 | Recombinant Chicken NR2E1 | Inquiry |
| Related Gene / Proteins | |||
| NR0B1 | NR2C2 | NR2E1 | NR2F2 |
| NR3C1 | NR4A3 | NRF1 | Nrf2 |
| NRIP1 | NRMT1 | NRU | |
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