Cat.No.: | EAb-1872 |
Product Name: | PBRM1 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This antibody was raised against a peptide within the N-terminal region of human PBRM1. |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 180 kDa |
Purification: | Affinity Purified |
Appearance: | Liquid |
Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
Applications: | ChIP-Seq: 7 µl (4 µg) per ChIP; WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human, Mouse |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | PBRM1 (polybromo 1) is a component of the SWI/SNF-B (PBAF) ATP-dependent chromatin-remodeling complex. It is involved in transcriptional activation and repression of select genes by chromatin remodeling and is an integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Defects in PBRM1 have been associated with primary clear cell renal cell carcinoma. |
Product Types | ||
◆ Cell Lines | ||
CL-0114 | Human PBRM1 Knockout Cell Line 8bp deletion | Inquiry |
◆ Proteins & Enzymes | ||
PE-1119 | Recombinant Zebrafish PBRM1L | Inquiry |
PE-1695 | PB1 (BD4), His-tag | Inquiry |
PE-1717 | PB1 (BD6), His-tag | Inquiry |
◆ Antibodies | ||
EAb-1869 | PBX2 Monoclonal Antibody | Inquiry |
Related Gene / Proteins | |||
PB1 | PBI | PBRM1 | PBRM1L |
PBX | PBX1b | PBX2 |
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