Phc2 Monoclonal Antibody


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Cat.No.:  EAb-1863
Product Name:  Phc2 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This Phc2 antibody was raised against a recombinant fragment of human Phc2.
Host:  Mouse
Isotype:  IgG
Molecular Weight:  90 kDa
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.
Applications:  ChIP; IP; ICC/IF; WB
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Phc2, polyhomeotic homolog 2 (also known as EDR2, early development regulatory protein 2) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc2 has been shown to interact with PHC1, BMI1, MAPKAPK2 and MCRS1.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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