| Cat.No.: | EAb-1858 |
| Product Name: | PIM2 Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This PIM2 antibody was raised against a recombinant protein corresponding to human PIM2. |
| Host: | Rat |
| Isotype: | IgG2a |
| Molecular Weight: | 37 kDa |
| Purification: | Protein G Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified rat IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | IHC: 2 µg/ml dilution; WB: 0.5 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-κB kinase/NF-κB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0053 | PIM1 Polyclonal Antibody | Inquiry |
| EAb-0326 | PIM1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0200 | Quercetin, Dihydrate | Inquiry |
| BSM-0223 | SMI-4a | Inquiry |
| BSM-0271 | CUDC-907 | Inquiry |
| Related Gene / Proteins | |||
| PI3K | PIAS2 | PIAS4 | PIASy |
| PID | PIM | PIM1 | PIM1 |
| PIM2 | PITX2 | PiwiL2 | PIWIL4 |
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