PRDM1 / BLIMP1 Monoclonal Antibody


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Cat.No.:  EAb-1853
Product Name:  PRDM1 / BLIMP1 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This PRDM1 / BLIMP1 antibody was raised against full-length recombinant human PRDM1 / BLIMP1 protein.
Host:  Mouse
Isotype:  IgG1
Molecular Weight:  77 and 95 kDa
Purification:  Protein G Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IHC; IP; WB
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  PRDM1 / BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1 / BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1 / BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1 / BLIMP1 also acts as a master regulator of intestinal maturation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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