| Cat.No.: | EAb-1799 |
| Product Name: | STAT5A/B phospho Tyr694/Tyr699 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This STAT5A/B phospho Tyr694/Tyr699 antibody was raised against a peptide containing phospho Tyr694 of human STAT5A. Human STAT5B shares the identical sequence surrounding Tyr699. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 92 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | STAT5A/B (signal transducer and activator of transcription 5) is a member of the STAT family of transcription factors. STATs undergo serine and tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. The STAT5 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNA1, IL-10, IL-6, IL-11, IL-12, IL-2, EGF, among others. Other members of the STAT family include STAT1α, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0164 | Human ST14 Knockout Cell Line | Inquiry |
| CL-0272 | Human STAMBP Knockout Cell Line 1bp insertion | Inquiry |
| CL-0273 | Human STAMBPL1 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0279 | Human STAMBPL1 Knockout Cell Line 2bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0178 | ST18 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| ST14 | ST18 | STAG1 | STAMBP |
| STAMBPL1 | STAT1 | STAT2 | STAT3 |
| STAT4 | STAT5A | STAT5B | STAT6 |
| STAU2 | STYXL1 | ||
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