| Cat.No.: | EAb-1790 |
| Product Name: | TCF7 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within the N-terminal region of human TCF7. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 52 and 55 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | TCF7 (Transcription Factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0079 | Recombinant Human TCF21 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0664 | Recombinant Chicken TCF21 | Inquiry |
| PE-0665 | Recombinant Zebrafish TCF21 | Inquiry |
| PE-0666 | Recombinant Mouse TCF21 Protein | Inquiry |
| PE-0667 | Recombinant Rhesus monkey TCF21 Protein, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| TCF21 | TCF4 | TCF7 | TCF7L1 |
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