| Cat.No.: | EAb-1781 |
| Product Name: | YY1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a recombinant protein corresponding to amino acids 249-414 of human YY1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 63 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP-Seq: 10 µl per ChIP; IP: 0.5 - 4 µl per IP; WB: 1:1,000 - 1:5,000 dilution; IHC (FFPE): 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | YY1 (Yin Yang 1) is a transcription factor that belongs to the GLI-Kruppel class of zinc finger transcription factors and is ubiquitously expressed. YY1 is known to have a fundamental role in normal biologic processes such as embryogenesis, differentiation, replication and cellular proliferation. YY1 exerts its effects on genes involved in these processes via its ability to initiate, activate or repress transcription depending upon the context in which it binds. Since expression and function of YY1 are known to be intimately associated with progression through phases of the cell cycle, the physiologic significance of YY1 activity has been applied to models of tumor biology. It can repress and activate a number of gene promoters and direct histone deacetylases (HDACs) and histone acetyltransferases (HATs). |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0075 | Recombinant Human YY1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0618 | Recombinant Human YY1, His-tagged | Inquiry |
| PE-0619 | Recombinant Human YY1 | Inquiry |
| PE-0620 | Recombinant Human YY1, FLAG-tagged | Inquiry |
| PE-0621 | Recombinant Human YY1, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| YY1 | |||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
