| Cat.No.: | EAb-1777 |
| Product Name: | XRCC1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a recombinant protein corresponding to the N-terminal region of human XRCC1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 85 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | ICC/IF: 1:2,000 dilution; WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | XRCC1 (X-ray repair complementing defective repair in Chinese hamster cells 1) corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase (PARP) to participate in the base excision repair (BER) pathway. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0002 | XRCC3 Polyclonal Antibody | Inquiry |
| EAb-0299 | XRCC3 Polyclonal Antibody | Inquiry |
| EAb-1777 | XRCC1 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0456 | Human XRCC4 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2742 | Recombinant Human XRCC3 protein (denatured) | Inquiry |
| Related Gene / Proteins | |||
| XRCC1 | XRCC3 | XRCC4 | |
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