UBE2C Polyclonal Antibody


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Cat.No.:  EAb-1630
Product Name:  UBE2C Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  IF, IHC, IP, WB
Recommended Dilutions/Conditions:  WB, IHC, IF, IP; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:100, IP 1:20 - 1:50
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  UBCH10, dJ447F3.2
Scientific Background:  UBE2C (ubiquitin-conjugating enzyme E2C) is a protein coding gene. Proteins modified with ubiquitin are able to target abnormal or short-lived proteins for degradation. Ubiquitination uses three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). UBE2C is necessary for the elimination of mitotic cyclins and for cell cycle progression, and is believed to be involved in cancer growth. Several transcript variants encoding different isoforms have been identified for this gene. Pseudogenes of this gene have been found on chromosomes 4, 14, 15, 18, and 19.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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