UBE2D1 Polyclonal Antibody


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Cat.No.:  EAb-1624
Product Name:  UBE2D1 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  IHC, WB
Recommended Dilutions/Conditions:  WB, IHC; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  SFT, UBCH5, UBC4/5, UBCH5A, E2(17)KB1
Scientific Background:  UBE2D1 (ubiquitin-conjugating enzyme E2D 1) is a protein coding gene. Proteins modified with ubiquitin are able to target abnormal or short-lived proteins for degradation. Ubiquitination uses three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). UBE2D1 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is similar to a stimulator of iron transport (SFT), and is also up-regulated in hereditary hemochromatosis. UBE2D1 functions in the ubiquitination of protein p53, a tumor-suppressor protein, and HIF1alpha by interacting with E1 and E3. Two transcript variants encoding different isoforms have been found for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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